Publications

  1. Morsut, L, Quadrato, G. Guiding human development in a dish. Nat. Methods. 2019;16 (7):585-586. doi: 10.1038/s41592-019-0464-1. PubMed PMID:31249404 .
  2. Velasco, S, Kedaigle, AJ, Simmons, SK, Nash, A, Rocha, M, Quadrato, G et al.. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019;570 (7762):523-527. doi: 10.1038/s41586-019-1289-x. PubMed PMID:31168097 .
  3. Brown, J, Quadrato, G, Arlotta, P. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. Curr. Top. Dev. Biol. 2018;129 :99-122. doi: 10.1016/bs.ctdb.2018.03.002. PubMed PMID:29801532 .
  4. Quadrato, G, Arlotta, P. Present and future of modeling human brain development in 3D organoids. Curr. Opin. Cell Biol. 2017;49 :47-52. doi: 10.1016/j.ceb.2017.11.010. PubMed PMID:29227864 .
  5. Quadrato, G, Nguyen, T, Macosko, EZ, Sherwood, JL, Min Yang, S, Berger, DR et al.. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545 (7652):48-53. doi: 10.1038/nature22047. PubMed PMID:28445462 PubMed Central PMC5659341.
  6. Quadrato, G, Brown, J, Arlotta, P. The promises and challenges of human brain organoids as models of neuropsychiatric disease. Nat. Med. 2016;22 (11):1220-1228. doi: 10.1038/nm.4214. PubMed PMID:27783065 .
  7. Quadrato, G, Zhang, AC, Arlotta, P. Stressed out? Healing Tips for Newly Reprogrammed Neurons. Cell Stem Cell. 2016;18 (3):297-9. doi: 10.1016/j.stem.2016.02.008. PubMed PMID:26942845 .
  8. Joshi, Y, Sória, MG, Quadrato, G, Inak, G, Zhou, L, Hervera, A et al.. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury. Brain. 2015;138 (Pt 7):1843-62. doi: 10.1093/brain/awv125. PubMed PMID:25981963 .
  9. Ottone, C, Krusche, B, Whitby, A, Clements, M, Quadrato, G, Pitulescu, ME et al.. Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells. Nat. Cell Biol. 2014;16 (11):1045-56. doi: 10.1038/ncb3045. PubMed PMID:25283993 PubMed Central PMC4298702.
  10. Quadrato, G, Elnaggar, MY, Duman, C, Sabino, A, Forsberg, K, Di Giovanni, S et al.. Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4. J. Neurosci. 2014;34 (25):8630-45. doi: 10.1523/JNEUROSCI.0047-14.2014. PubMed PMID:24948817 PubMed Central PMC6608211.